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. 2022 Jan 10;44(4):2007–2024. doi: 10.1007/s11357-022-00514-6

Table 3.

Baseline characteristics of eligible prospective cohort studies (2007–2020)

Author, year of publication Study Country Baseline year Average age, years Male % Average follow-up, years No. of participants HGS assessment Outcomes assessed Covariates adjusted for
Buchman, 2007 Religious Orders Study USA 1994–1996 74.4 30.7 5.7 877 Jamar handheld dynamometer AD Age, sex and education
Boyle, 2009 Rush Memory and Aging Project USA 1997–2005 80.3 24.8 3.6 970 Jamar handheld dynamometer AD Age, sex and education
Yamada, 2009 RERF’s Adult Health Study Japan 1992–1996 72.2 0.0 5.9 1637 NR Dementia and AD Age, age, education, BMI, smoking status, drinking status, menopausal age, and history of hypertension, DM or stroke
Boyle, 2010 Rush Memory and Aging Project USA 1997–2005 79.0 24.0 3.6 761 Jamar handheld dynamometer MCI Age, sex and education
Sattler, 2011 ILSE Germany 1993–1994 74.3 61.2 12.0 381 Martin-Vigorimeter MCI/AD Education, SES, gender and depressive symptoms
Gray, 2013 ACT USA 1994–1996/2002–2004 76.8 39.9 6.5 2619 Handheld dynamometer Dementia and AD Age, sex, education, race, BMI, depressive symptoms, antidepressant use, self-reported health, hypertension, DM, MI, CHF, and smoking status and baseline Cognitive Abilities Screening Instrument score
Veronese, 2016 Progetto Veneto Anziani Italy 1995–1997 72.2 40.4 4.4 1249 Jamar handheld dynamometer Cognitive decline and impairment Age, gender, BMI, preserved activities of daily living and instrumental activities of daily living, baseline scores in the Mini Mental State Examination and Geriatric Depression Scale; presence at the baseline of CVD, hypertension, osteoarthritis, fractures, chronic obstructive pulmonary disease, cancer; formal education; physical activity; smoking habits; monthly income
Camargo, 2016 Framingham Offspring USA 1999–2005 62.0 45.0 11.0 2176 Jamar handheld dynamometer Dementia and AD Age, sex, DM, SBP, CVD, AF, smoking, WHR, total cholesterol, apolipoprotein E4 allele, total plasma homocysteine and physical activity
Stessman, 2017 Jerusalem Longitudinal Cohort Study Israel 1990–1991 85.0 45.2 25.0 1187 5001 Grip-A handheld dynamometer Cognitive impairment Education, self-rated health, physical activity level, difficulty performing activities of daily living and DM
Sibbet, 2018 Lothian Birth Cohort 1921 UK 1999 79.0 42.6 9.7 488 Jamar handheld dynamometer Dementia FEV1, 6-m walk time, APOE ɛ4 carrier status, height, age, sex, history of hypertension, smoking status, age 11 IQ, history of cardiovascular or cerebrovascular disease and history of diabetes
Heward, 2018 IDEA Tanzania 2014 76.2 43.1 2.0 305 Jamar handheld dynamometer Cognitive decline Age and sex
McGrath, 2019 HRS USA 2006  ≥ 50* 8.0 13,828 Smedley handheld dynamometer Cognitive impairment Age, sex, race and ethnicity, BMI, morbidity, Center for Epidemiologic Studies Depression score, smoking history, current smoking status, physical activity, social engagement, time (wave), educational achievement and self-rated health
Kim, 2019 KLoSA South Korea 2006 63.4 45.5 8.0 5995 TANITA handheld dynamometer Cognitive impairment Time, baseline age, sex, education and quartiles of total household income as time-dependent covariates, time-varying smoking status, physical activity, alcohol consumption, obesity as time-dependent covariates, time-varying self-reported doctor diagnosis of co-morbidities, depressive symptoms and engagement in social activities as time-dependent covariates
Doi, 2019 NCG and GSGS Japan 2011–2012 72.0 48.0 3.6 4086 Smedley handheld dynamometer Dementia Age, sex, educational history, BMI, diseases, number of medications, falls, current smoking, alcohol consumption, cognitive function and physical inactivity
Hatabe, 2020 Hisayama study Japan 1988 68.0 42.6 14.6 1055 Smedley handheld dynamometer Dementia, AD and VD Age, sex, education level, SBP, use of antihypertensive agents, DM, total cholesterol, body mass index, electrocardiogram abnormalities, smoking habit, alcohol intake and regular exercise
Petermann-Rocha, 2020 UK Biobank UK 2006–2010 58.0 46.0 5.4 143,215 Jamar handheld dynamometer Dementia Age, sex, deprivation, ethnicity, education, leisure or social activities, frequency of friend and family visits, smoking, sleep duration, total discretionary sedentary time, alcohol intake, and consumption of red meat, processed meat, and fruit and vegetables, BMI, morbidity count, blood pressure, total cholesterol, glycated haemoglobin, reaction time at baseline and other components of sarcopenia
Current study KIHD Finland 1998–2001 69.0 47.4 16.6 852 Martin-Vigorimeter Dementia, AD and VD Age, sex, BMI, smoking status, history of type 2 DM, prevalent CHD, total cholesterol, HDL-C, physical activity and hsCRP

*Age range provided

AD Alzheimer’s disease, AF atrial fibrillation, BMI body mass index, CHD coronary heart disease, CHF congestive heart failure, CVD cardiovascular disease, DM diabetes mellitus, FEV1 forced expiratory volume, HDL-C high-density lipoprotein cholesterol, HGS handgrip strength, MCI mild cognitive impairment, MI myocardial infarction, NR not reported, SES socioeconomic status, SBP systolic blood pressure, VD vascular dementia, WHR waist-to-hip ratio

Study abbreviations: ACT, Adult Changes in Thought; HRS, Health and Retirement Study; IDEA, Intervention for Dementia in Elderly Africans; ILSE, Interdisciplinary Longitudinal Study on Adult Development and Aging;