Fig. 2.

Effects of GYY4137 or HMPSNE treatment on adipogenesis. A Scheme of GYY4137 or HMPSNE treatment during adipogenesis. B Representative images showing GYY4137-treated adipocytes stained with Oil Red O and C corresponding quantification on day 7 (fully differentiated state). D Representative images showing HMPSNE-treated adipocytes stained with Oil Red O and E corresponding quantification on day 7 (fully differentiated state). Data refer to mean values of N = 5 independent experiments ± SEM. *p < 0.05 and **p < 0.01 shows significant effect of HMPSNE or GYY4137 on Oil Red O accumulation on day 7 compared to control values in the absence of pharmacological modulator treatment