Figure 2. Association Between State-Issued Vaccine Mandates Shown as Adjusted Average Percentage Point Changes of COVID-19 Vaccine First-Dose Administration and Series Completion in 13 States With a Vaccine Mandate Relative to 14 Comparison Group States (May-October 2021).

A, State-issued vaccine mandates were defined as requirements for a group of workers to (1) be vaccinated with no test-out option except for those with approved medical or religious exemptions, or (2) be vaccinated and undergo recurring testing (for the states in each group, see the Inclusion Criteria subsection in the Methods section). B, Percentage point changes and 95% CIs estimated from regression models were controlled for state and time (calendar date) fixed effects, previous week rolling 7-day average new cases per 100 000 population, percentage of the population fully vaccinated, and whether the observation occurred before or after the mandate effective date. Percentage point changes are relative to the average growth rates for the referent category (14 comparison group states and the referent period of 0- 2 weeks before the mandate announcement date in states that issued a mandate) denoted by the vertical reference line. For the first-dose administrations model, the model-estimated referent category coverage was 62.9%. For the series completion model, the model-estimated referent category coverage was 56.3%. Shaded areas indicate 95% CI.