Table 5.
Comparison of Selected Structural Parameters Between Control and Glaucoma LC
| Mean ± SD | ||||
|---|---|---|---|---|
| Tissue Component | Structural Parameter | Control (n = 9) | Glaucoma (n = 16) | P |
| GFAP in pores | Area fraction (GFAP area/mask area) | 0.51 ± 0.04 | 0.48 ± 0.03 | 0.01* |
| Average process width (µm) | 1.60 ± 0.10 | 1.63 ± 0.09 | 0.42 | |
| F-actin in pores | Area fraction (F-actin area/mask area) | 0.48 ± 0.03 | 0.44 ± 0.04 | 0.07 |
| Average process width (µm) | 1.05 ± 0.03 | 1.07 ± 0.08 | 0.28 | |
| Nuclei overall | Median aspect ratio of nuclei | 2.04 ± 0.20 | 1.88 ± 0.13 | 0.02* |
| Axon compartments | Median of axonal area (µm2) | 0.64 ± 0.04 | 0.58 ± 0.07 | 0.05* |
*
Indicates significant P values from multivariable linear mixed-effect models.