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. 2022 Mar 30;75(9):1489–1496. doi: 10.1093/cid/ciac232

Table 3.

Logistic Regression Multivariable Model Identifying Risk Factors for Emergent Antiretroviral Therapy Resistance at 6 Months

Variable Univariate OR (95% CI) P Value Multivariable OR (95% CI) P Value
Agea 0.99 (0.93–1.05) .66 0.97 (0.90–1.05) .45
Male gender 2.11 (0.72–6.18) .17 3.89 (0.84–18.07) .083
CD4 T-cell count
≤200 cells/mL
4.51 (1.23–16.52) .022 5.21 (1.13–24.01) .034
On ART <6 months 2.72 (0.93–7.99) .068 3.08 (0.85 –11.21) .088
ART adherenceb (%) 0.96 (0.94-0.98) .0002 0.95 (0.93–0.98) .0002
Substance usec 0.62 (0.08–4.95) .65 0.72 (0.07–7.37) .78
History of opportunistic infections 0.61 (0.13–2.81) .52 0.38 (0.07–2.22) .28
Body mass index 0.90 (0.79–1.04) .15 0.97 (0.82–1.15) .76

Abbreviations: CI, confidence interval; OR, odds ratio.

Per year of increased age.

Per percent of increased adherence, cumulative adherence measured by electronic dose measuring through 6 months.

Substance use is defined as self-reported current use of psychoactive drugs, including alcohol, at baseline.