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. Author manuscript; available in PMC: 2023 Jul 7.
Published in final edited form as: Cell. 2022 Jun 22;185(14):2523–2541.e30. doi: 10.1016/j.cell.2022.05.024

Figure 7: Nipah and Hendra viruses elicit minimal transcriptional changes in artery endothelial cells, despite extensive viral replication and cell fusion.

Figure 7:

A) Percentage of hPSC-derived artery EC transcriptome comprising viral reads, as quantified by RNA-seq; averaged from H1 and SUN004.1.9 hPSCs

B) Transcriptome-wide differences between infected vs. uninfected artery ECs by RNA-seq; averaged from H1 and SUN004.1.9 hPSCs

C,D) RNA-seq of infected hPSC-derived artery ECs, including viral read percentage in transcriptome; averaged from H1 and SUN004.1.9 hPSCs

E) IFNβ secretion by hPSC-derived artery ECs; averaged from H1, SUN004.1.9 and SUN004.2 hPSCs; *P<0.05; n.s. = not significant

See also Figure S7 and Table S4