Figure 7.

Cortical ripple characteristics versus estimated hippocampo-cortical connectivity density. Cortical ripple density, peak 70-100 Hz analytic amplitude, oscillation frequency, duration, and >200 Hz amplitude modulation (N = 273 channels from Patients S1-S17) as a function of the connectivity density (Rosen and Halgren, 2021) between the hippocampus and each cortical parcel. The absence of significant correlations suggests that cortical ripples are related to corticocortical integration rather than being driven primarily by the hippocampus.