Table 3.

Cortical and hippocampal ripple characteristics by region in NREM and waking^a

Region	No. of patients	No. of channels	No. of ripples		Density (min−1)		Amplitude (µV)		Frequency (Hz)		Duration (ms)
			NREM	Waking	NREM	Waking	NREM	Waking	NREM	Waking	NREM	Waking
Orbitofrontal	6	14	129680	211957	9.01 ± 2.74	4.83 ± 3.26	1.38 ± 0.27	2.35 ± 1.23	88.8 ± 0.7	89.2 ± 0.9	74.4 ± 5.6	65.1 ± 3.1
Prefrontal	8	37	287124	609692	9.28 ± 2.66	6.62 ± 3.11	1.68 ± 0.60	2.19 ± 0.86	89.0 ± 0.7	89.5 ± 0.7	72.7 ± 4.9	64.4 ± 3.9
Rolandic	13	25	174262	315588	8.84 ± 2.57	6.36 ± 3.39	1.91 ± 0.95	2.88 ± 2.13	89.1 ± 0.8	89.5 ± 0.5	76.8 ± 13.5	66.0 ± 5.6
Parietal	16	79	491431	855766	8.18 ± 2.68	5.13 ± 3.45	1.84 ± 0.66	2.56 ± 1.15	89.3 ± 0.9	89.6 ± 0.6	76.6 ± 7.4	66.6 ± 5.9
Occipital	8	14	94144	103609	8.71 ± 2.91	4.55 ± 3.10	2.05 ± 0.77	3.12 ± 1.25	89.0 ± 0.6	89.7 ± 0.5	80.2 ± 9.9	65.4 ± 4.3
Superior temporal/insula	10	20	182981	324005	8.99 ± 2.08	7.90 ± 4.16	1.57 ± 0.64	2.49 ± 1.32	88.9 ± 0.8	89.7 ± 0.6	76.3 ± 15.8	65.2 ± 4.8
Lateral temporal	15	47	295324	534754	6.89 ± 2.61	4.95 ± 3.35	1.28 ± 0.74	1.98 ± 1.38	89.1 ± 0.9	89.5 ± 0.7	76.6 ± 12.7	66.3 ± 6.1
Ventral temporal	14	34	224478	417057	8.58 ± 2.64	6.54 ± 2.82	1.94 ± 0.82	2.73 ± 1.73	88.8 ± 0.7	89.2 ± 0.9	78.0 ± 6.9	69.7 ± 8.3
Cingulate	3	3	27078	42804	9.31 ± 1.84	7.00 ± 2.17	1.25 ± 0.85	1.55 ± 0.97	90.0 ± 0.0	89.8 ± 0.7	90.7 ± 27.7	87.7 ± 40.1
Mean (total) of cortical channels	17	273	1906502	3415232	8.36 ± 2.69	5.77 ± 3.42	1.70 ± 0.75	2.46 ± 1.39	89.1 ± 0.8	89.5 ± 0.7	76.5 ± 10.1	66.6 ± 7.2
Hippocampus	17	28	147138	409734	6.95 ± 4.80	7.40 ± 5.47	5.76 ± 2.58	6.00 ± 3.16	85.7 ± 2.0	88.2 ± 1.4	87.5 ± 9.0	69.7 ± 7.9

^aCortical parcellation scheme is specified in Table 2. Values are counts or mean ± SD across channels (N = 273 cortical, N = 28 hippocampal) from SEEG Patients S1-S17.