Table 9.
External gross malformations after treatment with the 80% ethanol fruit extract of Embelia schimperi.
| Group | Proportion of external malformations (%) | |||||||
|---|---|---|---|---|---|---|---|---|
| Nervous system defects | Musculoskeletal defects | Others | ||||||
| ExE | AnE | SB | KY | SC | LD | MT | EGA | |
| Group I (250 mg/kg) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Group II (500 mg/kg) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Group III (1000 mg/kg) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Group IV (pair-fed) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Group V (ad libitum) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results are expressed in terms of proportions of malformations, chi-square test; ExE: exencephaly, AnE: anencephaly, SB: spina bifida, KY: kyphosis, SC: scoliosis, LD: limb defect, MT: missed tail, and EGA: external genitalia agenesis.