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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Magn Reson Med. 2022 Sep 11;89(1):299–307. doi: 10.1002/mrm.29444

Table 1.

Comparison of T1, the exchange rate (ksw), and the relative labile proton ratio (fr) of amide protons before and after global ischemia (N = 6). ksw and fr values reported were from both omega plot on APT decoupled from globally averaged Z-spectrum and from IDEAL-based omega plot analysis on APT maps fitted using the IDEAL approach. Given a strong correlation between T1 and water content, the contribution of change in water proton towards fr has been normalized by T1. Mean ± standard deviation values were shown. Student’s t-tests were performed between live and postmortem conditions in the same brains with p values <0.05 denotes a statistically significant difference.

Live Postmortem P-value
T1 [s] 1.56 ± 0.012 1.65 ± 0.058 0.007
Globally averaged APT IDEAL fitted APT Globally averaged APT IDEAL fitted APT Globally averaged APT IDEAL fitted APT
ksw [s−1] 29.6 ± 5.6 29.9 ± 14.2 12.1 ± 1.3 11.2 ± 1.3 <0.001 0.009
fr × 10−3 2.42 ± 0.35 2.50 ± 0.30 2.02 ± 0.34 1.90 ± 0.40 0.074 0.034