Table 1.
Comparison of T1, the exchange rate (ksw), and the relative labile proton ratio (fr) of amide protons before and after global ischemia (N = 6). ksw and fr values reported were from both omega plot on APT decoupled from globally averaged Z-spectrum and from IDEAL-based omega plot analysis on APT maps fitted using the IDEAL approach. Given a strong correlation between T1 and water content, the contribution of change in water proton towards fr has been normalized by T1. Mean ± standard deviation values were shown. Student’s t-tests were performed between live and postmortem conditions in the same brains with p values <0.05 denotes a statistically significant difference.
| Live | Postmortem | P-value | ||||
|---|---|---|---|---|---|---|
| T1 [s] | 1.56 ± 0.012 | 1.65 ± 0.058 | 0.007 | |||
| Globally averaged APT | IDEAL fitted APT | Globally averaged APT | IDEAL fitted APT | Globally averaged APT | IDEAL fitted APT | |
| ksw [s−1] | 29.6 ± 5.6 | 29.9 ± 14.2 | 12.1 ± 1.3 | 11.2 ± 1.3 | <0.001 | 0.009 |
| fr × 10−3 | 2.42 ± 0.35 | 2.50 ± 0.30 | 2.02 ± 0.34 | 1.90 ± 0.40 | 0.074 | 0.034 |