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. Author manuscript; available in PMC: 2023 Nov 15.
Published in final edited form as: AIDS. 2022 Jul 16;36(14):1969–1978. doi: 10.1097/QAD.0000000000003333

Table 2:

Hazard ratios and 95% confidence intervals for selected variables showing association with 60-day and overall survival

Variable Hazard ratio for 60-day survival (95% confidence interval) P Hazard ratio for overall survival (95% confidence interval) P
Patient characteristics at ICU entry
 Age (above vs. below median) 0.83 (0.25, 2.71) 0.75 0.89 (0.42, 1.89) 0.76
 CD4 count (<100 vs. ≥100) 1.35 (0.41, 4.42) 0.62 0.77 (0.34, 1.72) 0.52
 HIV VL (<25 vs. ≥25) 0.37 (0.10, 1.39) 0.14 1.00 (0.47, 2.15) 0.99
 SOFA score (<6 vs. ≥6) 1.73 (0.51, 5.91) 0.38 1.43 (0.66, 3.09) 0.37
 KSHV VL (above vs. below median) 1.82 (0.48, 6.89) 0.37 1.44 (0.66, 3.16) 0.37
 KAD diagnoses at ICU discharge or death
 MCD +/− KS 0.28 (0.04, 2.15) 0.21 0.59 (0.22, 1.57) 0.29
 KICS +/− KS 0.82 (0.22, 3.09) 0.77 1.35 (0.59, 3.08) 0.47
 PEL +/− MCD +/− KS 3.37 (0.99, 11.55) 0.05 2.03 (0.95, 4.35) 0.07
ICU Interventions
 Vasopressors 3.25 (0.86, 12.25) 0.08 2.23 (1.02, 4.88) 0.05
 Mechanical ventilation 4.95 (1.44, 16.96) 0.01 2.99 (1.29, 6.97) 0.01
 Chemotherapy or other for KAD 3.22 (0.85, 12.14) 0.85 1.54 (0.71, 3.32) 0.27
Cytokines at admission to ICU – (above vs. below median)
 Interferon-γ, pg/mL 1.29 (0.34, 4.85) 0.71 1.65 (0.68, 4.02) 0.27
 IL-10, pg/mL 1.33 (0.35, 5.03) 0.67 1.14 (0.51, 2.56) 0.75
 IL-12, pg/mL 0.82 (0.24, 2.82) 0.76 1.06 (0.47, 2.37) 0.90
 IL-13, pg/mL 0.40 (0.12, 1.32) 0.13 0.67 (0.31, 1.43) 0.30
 IL-1β, pg/mL 0.65 (0.20, 2.12) 0.47 0.77 (0.36, 1.71) 0.54
 IL-2, pg/mL* 1 (NA) NA 1 (NA) NA
 IL-4, pg/mL 1.30 (0.35, 4.91) 0.70 1.43 (0.62, 3.28) 0.40
 IL-6, pg/mL 1.33 (0.35, 5.03) 0.67 1.79 (0.76, 4.22) 0.19
 IL-8, pg/mL 0.71 (0.21, 2.41) 0.58 0.54 (0.25, 1.15) 0.11
 TNF-α, pg/mL 0.74 (0.22, 2.53) 0.63 0.84 (0.38, 1.85) 0.66
*

No values below median