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. 2022 Oct 29;40(1):4. doi: 10.1007/s12032-022-01790-0

Table 1.

PICO elements used to determine studies eligible for inclusion within results of this review

Element Focus
Population Adult patients with early/resectable NSCLC (stage I–III) in the locoregional recurrence health state
Interventions/comparators

● Atezolizumab

● Pemetrexed

● Nab-paclitaxel

● Gemcitabine

● Vinorelbine

● Nivolumab

● Durvalumab

● Cemiplimab

● Avelumab

● Tegafur ± uracil (UFT)

● Osimertinib

● Pembrolizumab

● Erlotinib

● Cisplatin-based chemotherapy

● Carboplatin-based chemotherapy

● Gefitinib

● Afatinib

● Docetaxel

● Radiotherapy

● Best supportive care

● Etoposide

● Surgery

Outcomes

● Treatment patterns in locoregional recurrence (including palliative and supportive care)

● Survival outcomes for locoregional recurrence

Study design Prospective and retrospective observational studies

QoL quality of life