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. 2022 Oct 29;12:18223. doi: 10.1038/s41598-022-23050-x

Table 1.

IC50 values (µg/ml) of Fluorophenyl-isoxazole-carboxamide compounds and positive controls on DPPH, α-amylase, and lipase enzyme.

graphic file with name 41598_2022_23050_Figa_HTML.gif IC50 (µg/ml)
Code R Group DPPH Lipase α-Amylase
2a graphic file with name 41598_2022_23050_Figb_HTML.gif 0.45 ± 0.21  > 400  > 500
2b graphic file with name 41598_2022_23050_Figc_HTML.gif 43.85 ± 0.71 358.18 ± 1.32  > 500
2c graphic file with name 41598_2022_23050_Figd_HTML.gif 0.47 ± 0.33  > 400  > 500
2d graphic file with name 41598_2022_23050_Fige_HTML.gif 5.11 ± 0.91 303.90 ± 2.2  > 500
2e graphic file with name 41598_2022_23050_Figf_HTML.gif 33.39 ± 0.57  > 400  > 500
 + ve control 3.10 ± 0.92a 12.30 ± 0.33b 28.84 ± 1.22c

P value ≤ 0.05.

aTrolox,

bOrlistat,

cAcarbose.