Skip to main content
. 2022 Oct 29;5:1149. doi: 10.1038/s42003-022-04150-w

Fig. 8. Overexpression of E-cadherin in AT2 protects against elastase-induced injury.

Fig. 8

No difference in a total lung capacity, b residual volume, and c compliance among mice overexpressing E-cadherin in AT2 cells (Cdh1Oe-SpcCre) instilled with elastase as compared to Cdh1Oe-SpcCre with PBS and wild-type (Wt) instilled with elastase. d H&E staining (representative image) and e quantitative MLI showed a reduction in airspace enlargement as compared to Cdh1Oe-SpcCre instilled with PBS and Wt instilled with elastase. Data are expressed as median bars and generated from 5 to 14 mice. Kruskal-Wallis test, followed by Dunn’s multiple comparison test was performed. P < 0.05 were considered statistically significant.