Table 1.

Prevalence and number in HBsAg-negative and HBcAb-positive US adults, 2001–2018 (weighted)

	NHANES 2001–2018 (Total)	NHANES 2001–2006 (Era 1)	NHANES 2007–2012 (Era 2)	NHANES 2013–2018 (Era 3)
Number of US adults, in millions (95% CI)	220.82 (212.88–228.76)	208.98 (194.94–223.02)	219.36 (204.9–233.82)	234.13 (221.34–246.86)
Prevalence of HBsAg-negative and HBcAb-positive, % (95% CI)	4.46 (4.17–4.75)	5.19 (4.69–5.68)	4.15 (3.67–4.62)	4.27 (3.77–4.76)
Number of HBsAg-negative and HBcAb-positive adults, in millions (95% CI)	9.87 (9.23–10.50)	10.85 (9.81–11.89)	9.11 (8.07–10.15)	10.00 (8.84–11.16)

All estimates accounted for complex survey designs and sampling weights of NHANES