Table 1.
Maternal and neonatal characteristics and outcomes of preterm infants enrolled in this study
| Variables | EOS n = 108 |
Non-EOS n = 5757 |
P value |
|---|---|---|---|
| Neonatal characteristics | |||
| Birthweight, g (median, IQR) | 1300 (1100, 1540) | 1370 (1170, 1580) | 0.029 |
| GA, week (median, IQR) | 29 (28, 30) | 30 (29, 31) | 0.001 |
| Apgar 1 min score, mean (SD) | 6.59 (2.48) | 7.15 (2.30) | 0.001 |
| Apgar 5 min score, mean (SD) | 7.81 (1.88) | 8.15 (1.81) | 0.009 |
| Female, n (%) | 50 (46.3) | 2261 (51.4) | 0.164 |
| SGA, n (%) | 5 (4.6) | 518 (9.0) | 0.126 |
| Fetal tachycardia, n (%) | 4 (3.7) | 356 (6.2) | 0.415 |
| Multiple birth, n (%) | 29 (26.9) | 1358 (23.6) | 0.425 |
| Maternal characteristics | |||
| Mother’s age, mean (SD) | 32 (4.46) | 31 (8.01) | 0.494 |
| Caesarean section, n (%) | 71 (65.6) | 3995 (69.4) | 0.402 |
| Antenatal steroid, n (%) | 92 (85.1) | 4024 (69.9) | 0.000 |
| Antepartum antibiotic, n (%) | 48 (44.4) | 2245 (39.0) | 0.274 |
| Rupture of membrane ≥ 18 h, n (%) | 26 (24.0) | 720 (12.5) | 0.001 |
| Outcome of infants | |||
| Mortality, n (%) | 18 (16.7) | 524 (9.1) | 0.011 |
| EUGR, n (%) | 48 (44.4) | 1877 (32.6) | 0.013 |
| BPD, n (%) | 24 (22.2) | 524 (9.1) | 0.000 |
| IVH, n (%) | 6 (5.5) | 86 (1.5) | 0.007 |
| NEC, n (%) | 1 (0.9) | 86 (1.5) | 1.000 |
| ROP, n (%) | 3 (2.8) | 391 (6.8) | 0.119 |
GA gestational age, SGA small for gestational age, EUGR extrauterine growth retardation, BPD bronchopulmonary dysplasia, IVH intraventricular hemorrhage, NEC necrotizing enterocolitis, ROP retinopathy of prematurity