Table 1.
Demographic, neuropsychological, and behavioral variables across the robustly cognitively intact sample (n = 674) and validation samples (ns = 439 and 728)
| Robustly cognitively intact sample | Validation sample | |||||
|---|---|---|---|---|---|---|
| Cognitively Intact | MCI | |||||
| n | 674 | 439 | 728 | |||
| Variable | Mean (SD) | Range | Mean (SD) | Range | Mean (SD) | Range |
| Age (years) | 71.86 (6.4) | 55–89 | 72.00 (7.1) | 55–88 | 73.11 (7.4) | 54–89 |
| Education (years) | 16.43 (2.6) | 6–20 | 16.23 (2.6) | 7–20 | 16.03 (2.9) | 4–20 |
| Sex (% female) | 54.7% | 53.3% | 36.7% | |||
| Race (% Caucasian) | 92.1% | 84.1% | 86.8% | |||
| GDS | 1.02 (1.3) | 0–6 | 1.17 (1.3) | 0–6 | 1.62 (1.5) | 0–6 |
| AMNART VIQ | 120.76 (7.2) | 86–131 | 119.25 (9.2) | 86–131 | 115.86 (9.8) | 84–131 |
| MMSE | 29.00 (1.2) | 23–30 | 28.62 (1.5) | 19–30 | 27.35 (1.9) | 19–20 |
| CDR-SB | 0.34 (0.6) | 0–3.5 | 0.56 (0.8) | 0–4 | 1.57 (1.0) | 0–6 |
| FAQ | 0.40 (1.0) | 0–8 | 0.90 (1.8) | 0–8 | 3.84 (4.58) | 0–24 |
| RAVLT LR score | 0.68 (0.2) | 0.00–1.00 | 0.60 (0.2) | 0.00–1.00 | 0.39 (0.2) | 0.00–1.00 |
| RAVLT RLS score | 6.40 (2.2) | 1–12 | 5.84 (2.3) | 1–12 | 4.13 (2.2) | 1–11 |
| RAVLT LOT score | 18.36 (7.5) | −3 – 39 | 16.32 (7.7) | −3 – 46 | 10.60 (6.9) | −7 – 39 |
| RAVLT Trial 1 score | 5.49 (1.7) | 1–13 | 5.09 (1.9) | 0–13 | 4.23 (1.6) | 0–10 |
Note: MCI = mild cognitive impairment, SD = standard deviation, GDS = Geriatric Depression Scale, AMNART VIQ = American National Adult Reading Test Verbal Intellectual Quotient, MMSE = Mini-Mental State Examination, CDR-SB = Clinical Dementia Rating scale-Sum of Boxes, FAQ = Functional Activity Questionnaire, RAVLT = Rey Auditory Verbal Learning Test, LR = learning ratio, RLS = Raw Learning Score, LOT = learning over trials. AMNART VIQ Mean score listed as a Standard Score. LR calculated using the equation (Highest Trial Score [of Trials 2 through 5] – Trial 1)/(Total Points Available for a Trial – Trial 1). RLS calculated using the equation (Highest Trial Score [of Trials 2 through 5] – Trial 1). LOT calculated using the equation (Sum of Trials 1 through 5 – (Trial 1 × 5)). Note, the Robustly Cognitively Intact sample was used for all primary analyses, and the Validation sample was used to validate the demographically adjusted normative equations.