Table 2.
Top 10 significant hypermethylated positions in Stanford-A AAD compared to healthy control
| CpG site | Gene | Chr | Gene region | Location | △Beta | P values |
|---|---|---|---|---|---|---|
| cg14065526 | NOTCH1 | chr9 | Body | S_Shore | 0.440 | <0.001 |
| cg05276972 | 0.692 | <0.001 | ||||
| cg26296371 | FARS2 | Body | 0.505 | <0.001 | ||
| cg26707845 | ODZ4 | Body | 0.345 | <0.001 | ||
| cg08224682 | 0.388 | <0.001 | ||||
| cg03025413 | 0.410 | <0.001 | ||||
| cg12524725 | 0.308 | <0.001 | ||||
| cg06043710 | DIP2C | Body | 0.329 | <0.001 | ||
| cg14757661 | 0.316 | <0.001 | ||||
| cg05877990 | 0.307 | <0.001 |
Abbreviations: S-Shore, South shore which are regions flanking island; Chr, Chromosome. AAD, Acute aortic dissection