Fig. 3.

Occurrence of incident cardiovascular outcomes during follow up (a) Incidence of total cardiovascular outcome by the age at enrollment (b) Incidence of each cardiovascular outcomes p value: Adjusted for age at enrollment, race, BMI, smoking, alcohol consumption, early menopause, hysterectomy, prevalent comorbidities (hypertension, diabetes, dyslipidemia) and medication by Cox regression analysis CAD coronary artery disease, MI myocardial infarction, PAD peripheral artery disease, AS aortic stenosis, MR mitral regurgitation, Afib atrial fibrillation, Aflutter atrial flutter, VTE venous thromboembolism