Fig. 1.

Knockdown of Rab4 effectively increases exosome secretion. A Schematic illustration of exosome biogenesis. B Schematics illustrating the workflow for screening genes boosting exosome yield. C Effects of siRNA on exosome production. AML12 cells were transfected with indicated siRNAs and the derived exosomes were calculated by NTA. All data are expressed as mean $\pm$ SEM of triplicate experiments. *p < 0.05