Table 1.

Overall effect of vascular risk factors on global neurocognitive impairment

Variable	I2 (%)	k	# of effect sizes	OR	log(OR)	p	95% CI	df
Unadjusted intercept	59.28	11	26	2.059**	0.722	.009	[1.288–3.287]	5.65
Adjusted intercept	-	9	24	2.136*	0.759	.017	[1.351–3.989]	2.30
AIDS (proportion)	-	-	-	2.239	0.806	.611	[0.005–1009.59]	1.88
Nadir CD4 (cells/microliter)	-	-	-	1.008	0.008	.335	[0.984–1.033]	2.58
HIV duration (mean/median)	-	-	-	0.971	−0.029	.669	[0.005–1009.59]	2.51

Note: The unadjusted intercept value is the overall effect size. Adjusted intercept refers to overall effect size after accounting for listed covariates. Models with degrees of freedom <4 are not trustworthy. All models were run separately and estimated using robust variance estimation meta-analysis. Abbreviations: k = number of outcomes included in the categoryOR = odds ratio; CI = confidence interval of the OR; df = degree of freedom; AIDS = acquired immune-deficiency syndrome; HIV duration = human immunodeficiency virus years since diagnosis.

^**p < .01.

^*p < .05.