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Schematic illustration of the tentative mechanism for alleviation of arterial restenosis by hiPSC-EC-EV treatment in mice via the miR-126-mediated autophagy regulation. Intravenously (iv)-injected hiPSC-EC-EV enriched in miR-126 could accumulate on the surface of the carotid artery endothelium, and suppress apoptosis in the ECs via autophagy upregulation.
