REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological samples
Serum samples	Beijing Anzhen Hospital	https://www.anzhen.org/
Chemicals, peptides, and recombinant proteins
LC-MS grade acetonitrile	Fisher Scientific	Cat # A955-4
LC-MS grade methanol	Fisher Scientific	Cat # A456-4
LC-MS grade formic acid	Fisher Scientific	Cat # A117-50
L-phenyl-d5-alanine	Sigma-Aldrich	Cat # 615870
L-leucine-5, 5, 5-d3	Sigma-Aldrich	Cat # 486825
Stearic acid-18, 18, 18-d3	Sigma-Aldrich	Cat # 490393
Cholic acid-2, 2, 4, 4-d4	Sigma-Aldrich	Cat # 903809
L-arginine-d7	Cayman Chemical	Cat # 34834
PC (18:0/20:4)-d11	Cayman Chemical	Cat # 27928
Stearoyl-L-carnitine-d3	Cayman Chemical	Cat # 26580
Cholesterol-d7	Cayman Chemical	Cat # 25265
LysoPC (19:0)-d5	Avanti Polar Lipids, Inc.	Cat # 855778
Critical commercial assays
TC	Tellgen Corporation.	BH016Z
TG	Tellgen Corporation.	BH017Z
APOB	Tellgen Corporation.	BH021Z
HDL	Tellgen Corporation.	BH018Z
LDL	Beijing Strong Biotechnologies, Inc.	EGS141Z
Lp(a)	Beijing Strong Biotechnologies, Inc.	GM9151Z
Deposited data
LC-MS raw data	This paper	https://service.most.gov.cn/
Software and algorithms
Progenesis QI software	Waters, Manchester, U.K.	https://www.waters.com/waters/en_US/Progenesis-QI-Software
SIMCA-P software	Umetric, Umeå, Sweden	https://www.sartorius.com/
SPSS Statistics	IBM Corp, New York, USA	N/A
MetaboAnalyst	https://www.metaboanalyst.ca	N/A
Bioinformatics platform	http://www.bioinformatics.com.cn/login/	N/A