Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 17;13:1002363. doi: 10.3389/fphar.2022.1002363

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Wang, Ali, Liu, Cheng, Wu, Saleem, Zheng, Wei, Chu, Xie, Shen and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Quercetin attenuates angiotensin-II-induced JAK2/STAT3 activation. (A–B) Protein expression of JAK2 and STAT3 along with p-JAK2 and p-STAT3 expression levels was analyzed by western blotting in VSMCs with or without 0.1 µM Ang II-induction and quercetin (12.5 µM) treatment for 24 h (A) JAK2 and p-JAK2 protein levels in VSMCs Ang II-induced cells treated with quercetin and quantification of the expression level of p-JAK2/JAK2 (represented in right panel graph) (B) STAT3 and p-STAT3 protein levels in VSMCs Ang II-induced cells treated with quercetin and quantification of the expression level of p-STAT3/STAT3 (represented in right panel graph. Data are presented as mean ± SD; n = 3 for in vitro study; *p < 0.05 vs. Control group, #p < 0.05 vs. Ang II group.