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. 2022 Oct 17;13:987227. doi: 10.3389/fimmu.2022.987227

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Copyright © 2022 Chen, Zhu, Deng, Yao, Zhang, Liu, Tang and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphological features of CD8-predominant AITL. In the hematoxylin & eosin staining, the CD8-predominant AITL exhibited (A) effaced lymph node architecture (×10), (B) in a diffuse growth pattern (×40), (C) with arborizing HEV proliferation (×200) and (D) eosinophil increase (×200). (E) Medium-sized (×400) or (F) medium-large-sized (×400) neoplastic T-cells with clear to pale cytoplasm surrounding HEVs.