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. 2022 Oct 17;13:987227. doi: 10.3389/fimmu.2022.987227

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Copyright © 2022 Chen, Zhu, Deng, Yao, Zhang, Liu, Tang and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of TRB and IGH repertoires between CD8-predominant AITLs and matched common AITLs. Comparison between two AITL groups TME in statistical metrics including production clones, V-gene family usage, top 10 clones’ proportion, clonality score, and entropy of TRB repertoire (A) and IGH repertoire (D), in global usage of V-gene of TRB repertoire (B) and IGH repertoire (E), and in the CDR3 sequence frequency of the TRB (C) and IGH repertoires (F). “ns” indicates “no significance”.