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. 2022 Oct 17;13:1008275. doi: 10.3389/fendo.2022.1008275

Table 3.

Association between Average caffeine intake (g/day) and lumbar bone mineral density (g/cm2), stratified by age and gender.

Quintiles of average caffeine intake (g/day) Lumbar bone mineral density (g/cm2), β (95% Cl)
Male Female
20–29 years old 0.025 (-0.029, 0.078) 0.056 (-0.012, 0.125)
Lowest quartiles reference reference
2nd 0.004 (-0.017, 0.025) -0.007 (-0.026, 0.012)
3rd -0.003 (-0.024, 0.019) 0.006 (-0.013, 0.026)
4th -0.019 (-0.042, 0.003) 0.014 (-0.008, 0.036)
P for trend 0.096 0.158
30–39 years old 0.023 (-0.024, 0.071) 0.080 (0.019, 0.142)*
Lowest quartiles reference reference
2nd -0.006 (-0.033, 0.020) 0.009 (-0.014, 0.033)
3rd -0.012 (-0.037, 0.012) 0.012 (-0.013, 0.036)
4th 0.003 (-0.020, 0.026) 0.025 (0.000, 0.050)*
P for trend 0.748 0.049
40–49 years old -0.070 (-0.113, -0.026)** 0.007 (-0.041, 0.054)
Lowest quartiles reference reference
2nd 0.001 (-0.032, 0.033) 0.013 (-0.015, 0.040)
3rd 0.016 (-0.018, 0.049) 0.020 (-0.007, 0.047)
4th -0.027 (-0.058, 0.004) 0.011 (-0.016, 0.037)
P for trend 0.026 0.553

All variables were adjusted.

*P<0.05, **P<0.01.