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. 2022 Aug 8;11:334–349. doi: 10.1016/j.aninu.2022.07.013

Table 2.

A summary of some studies that have shown effects when insects were used as a protein source in aquafeed.

Insect species Used part Aquaculture species Fish weight, g Period Inclusion level, % Effect References
Black soldier fly (Hermetia illucens) Frass Hybrid tilapia, Nile × Mozambique (Oreocromis niloticus × O. mozambique) 2.6 ± 0.04 12 wk 5 to 30 Improved protein efficiency, serum complement activity and resistance against Flavobacterium columnare and Streptococcus iniae Yildirim-Aksoy et al. (2020)
Meal Rice field eel (Monopterus albus) 24.0 ± 0.02 10 wk 15.78 Improved growth performance and gut microbiota balance Hu et al. (2020)
Meal Atlantic salmon (Salmo salar) 17.5 ± 7.5 8 wk 66 to 100 Down-regulation of stress and antioxidant-related gene expression in the leucocytes. Stenberg et al. (2019)
Defatted meal Japanese seabass (Lateolabrax japonicus) 14.1 ± 0.17 8 wk 64 Enhanced feed intake but lowered serum properties, blood lipid and inhibited lipid deposition Wang et al. (2019)
Meal African catfish (Clarias gariepinus) 4.0 ± 0.01 60 d 50 Improved growth performance and feed utilization and antioxidant enzymes. Fawole et al. (2020)
Meal European sea bass (Dicentrarchus labrax) 50.0 ± 0.50 62 d 22.5 Reduced lipid oxidation in the fillet Moutinho et al. (2021)
Meal Rainbow trout (Oncorhynchus mykiss) 32.0 10 wk 8 to16 Successful prevention of soybean meal (SBM)-induced enteritis in the intestine and enhanced immune response Kumar et al. (2021)
Oil Rainbow trout 32.0 10 wk 16 Improved serum-peroxidase activity and upregulation of kidney interleukin-8 (IL-8), tumour necrosis factor (TNF), and interferon regulatory factor 1 (IRF-1) Kumar et al. (2021)
Meal Pre-smolt Atlantic salmon 49.0 ± 1.50 8 wk 85 Reduced the deposition of excess lipids in the pyloric caeca and stimulated xenobiotic metabolism. Li et al. (2019)
Meal Rainbow trout 137.0 ± 10.50 98 d 50 Activation of immune related genes such as interleukin 10 (IL-10), TNF-α and toll-like receptor 5 (TLR-5) Cardinaletti et al. (2019)
Meal Pacific white shrimp (Litopenaeus vannamei) 0.67 ± 0.15 4 wk 7.5 Improved weight gain, feed conversion ratio (FCR) and specific growth rate (SGR) Richardson et al. (2021)
Meal Barramundi (Lates calcarifer) 1.74 ± 0.15 42 d 30 Improved growth and feed utilization, bactericidal activity and upregulation of immune-related genes such as interleukin 1 (IL-1) and IL-10 Hender et al. (2021)
Oil Barramundi 1.74 ± 0.15 42 d 30 Enhanced growth performance and upregulation of immune-related genes (IL-1 and IL-10) Hender et al. (2021)
Partially defatted meal Rainbow trout 178.9 ± 9.81 78 d 50 Sensitivity and modulation of intestinal bacterial community and structure. Bruni et al. (2018)
Meal Atlantic salmon 49.0 ± 1.5 8 wk 60 Modulation of intestinal microbiota, enrichment of beneficial bacteria Li et al. (2021)
Meal Atlantic salmon 1400 ± 43 16 wk 15 Improved microbial richness and diversity related to immune responses and barrier function in the distal intestine
Oil Mirror carp (Cyprinus carpio var. specularis) 2.74 8 wk 50 to 100 Enhanced growth and feed utilization and health parameters Xu et al. (2020a)
Meal Atlantic Salmon 34 7 wk 12.5 Reduction in enterocyte steatosis in pyloric caeca improved distal intestine histology and enhanced plasma lysozyme content Weththasinghe et al. (2021)
Meal Rainbow trout 201.8 ± 13.9 5 wk 30 Increased diversity and modulation of gut bacteria composition Huyben et al. (2019)
Pulp Mirror carp 13.68 ± 0.02 8 wk 50 Decreased whole-body lipid content and increased antioxidant enzyme activity
Meal Rainbow trout 100 131 d 50 Modulation of the gut microbial community by enhancing the abundance of bacteria taxa related to fish health Rimoldi et al. (2021)
Meal Baltic prawn (Palaemon adspersu) 0.49 ± 0.1 60 d 18 Improved growth performance and survival Mastoraki et al. (2020)
Meal Siberian sturgeon (Acipenser baerii) 640 ± 3.9 60 d 15 Improved gut microbiota composition and intestinal morphology but reduced mucosa thickness in the gastrointestinal tract. Józefiak et al. (2019b)
Meal Siberian sturgeon 60 d 50 Lowered diet acceptance results in lowered growth and survival, decreased hepatic lipids and glycogen content, adverse effects on gut histology, but with a higher hepatic heat shock protein 70.1 (hsp70.1) gene expression Zarantoniello et al. (2021)
Meal Rainbow trout 53.4 ± 3.74 71 d 20 Improved growth performance and an increased count of beneficial bacteria in the intestine Józefiak et al. (2019a)
Silkworm (Bombyx mori L.) pupae Defatted meal Pacific white shrimp (L. vannamei) 0.2 ± 0.02 8 wk 75 to 100 Improved digestibility, antioxidant capacity and reduced molting time. Rahimnejad et al. (2019)
Mealworm beetle, (TM) Meal Giant river prawn (Macrobrachium rosenbergii) 3.26 ± 0.13 10 wk 12 Improved growth performance, immune response, disease resistance against Lactococcus garvieae, and Aeromonas hydrophila. Feng et al. (2019)
Defatted meal Pacific white shrimp 1.5 to 1.6 8 wk 50 Improved growth and feed conversion ratio, enhanced resistance against early mortality syndrome (Vibrio parahaemolyticus) Motte et al. (2019)
Partially defatted meal Rainbow trout 78.3 ± 6.24 154 d 50 to 100 Reduced apparent digestibility of crude protein Chemello et al. (2020)
Meal Gilthead seabream (Sparus aurata) 105.2 ± 0.17 163 d 50 Establishment of novel nutritional niches in the gut Antonopoulou et al. (2019)
Meal Gilthead seabream 86.97 ± 2.3 163 d 25 Best final weight, specific growth rate, weight gain, protein efficiency ratio and a lower feed conversion ratio Piccolo et al. (2017)
Meal European sea bass 5.2 ± 0.82 70 d 50 Establishment of novel nutritional niches in the gut Antonopoulou et al. (2019)
Meal Rainbow trout 115.2 ± 14.21 90 d 60 Improved specialized gut bacterial community Antonopoulou et al. (2019)
Defatted meal Red seabream (Pargus major) 30.4 8 wk 10 Increased resistance against pathogenic Edwardsiella tarda bacteria Ido et al. (2019)
Meal Rainbow trout 115.6 ± 14 90 d 50 Increased activity of the antioxidant enzymes in the intestine and reduction of lipid peroxidation. Also increased antibacterial activity of the serum Henry et al. (2018)
Meal European sea bass 65.3 ± 5.7 6 wk 25 Enhanced lysozyme antibacterial activity and serum trypsin inhibition linked to the anti-parasite activity of the fish. Henry et al. (2018)
Meal Rainbow trout 105.2 ± 0.17 163 d 50 Reduction in some essential amino acids (Ala, Ile, Leu, and Lys). Iaconisi et al. (2019)
Meal Rainbow trout 1.11 ± 0.01 8 wk 14 Improved growth performance and lysozyme activities Jeong et al. (2020)
Meal Baltic prawn (P. adspersu) 0.49 ± 0.1 60 d 18 Higher protein and energy contents in the muscles Mastoraki et al. (2020)
Meal Siberian sturgeon 640 ± 3.9 60 d 15 Increased thickness of the muscular layer in the gastrointestinal tract and decreased the total number of bacteria Józefiak et al. (2019b)
Partially defatted Rainbow trout 78.3 ± 6.24 22 wk 100 Slight modulation observed in the gut and skin microbiota by reducing pathogenic bacteria count Terova et al. (2021)
Meal Mandarin fish (Siniperca scherzeri) 20.8 ± 0.05 8 wk 30 Improved growth and feed efficiency and enhanced serum lysozyme and glutathione peroxidase (GPx) activities. Sankian et al. (2018)
Meal Yellow catfish (Pelteobagrus fulvidraco) 10.0 ± 0.03 5 wk 18 Enhanced immune response and disease resistance against Edwardsiella ictaluri Su et al. (2017)
Meal Rainbow trout 53.4 ± 3.74 71 d 20 Improved growth performance, reduced villus height and increased count of beneficial bacteria in the intestine Józefiak et al. (2019a)
Meal White shrimp 2.39 ± 0.49 8 wk 100 Enhanced the weight gain, specific growth rate and feed conversion rate Choi et al. (2018)
Meal Narrow-clawed crayfish (Pontastacus leptodactylus) 0.011 ± 0.002 80 d 50 Improved weight gain, specific growth rate, protein efficiency ratio, apparent net protein utilization, molting frequency, and feed conservation ratio, but lower survival rate as compared to the other diet groups. Also improved protein and lipid content of the whole body Mazlum et al. (2021)
Meal Black porgy, (Acanthopagrus schlegelii) 6.43 ± 0.00 12 wk 60 Improved serum lysozyme activity and upregulation of antioxidant enzyme-related genes but with declined fillet lipid content Jeong et al. (2022)
Superworm larvae (Zophobas morio) Meal Nile tilapia 3.00 ± 0.2 12 wk 15 Enhanced innate immune parameters (thrombocytes and neutrophils), liver and serum lysozyme activity, and complement system activity Alves et al. (2021)
Housefly (Musca domestica) Meal Baltic prawn (P. adspersu) 0.49 ± 0.1 60 d 18 Enhanced growth performance but lowered survival Mastoraki et al. (2020)
Cricket (Gryllus bimaculatus) Meal African catfish 13.2 ± 0.3 7 wk 100 Improved growth performance, haemoglobin, haematocrit and catalase activity Taufek et al. (2016)
Tropical house cricket (Gryllodes sigillatus) Meal Rainbow trout 53.4 ± 3.74 71 d 20 Lowered growth performance, reduced villus height and increased count of beneficial bacteria in the intestine Józefiak et al. (2019a)
Turkestan cockroach (Blatta lateralis) Meal Rainbow trout 53.4 ± 3.74 71 d 20 Improved growth performance, increased villus height and count of beneficial bacteria in the intestine Józefiak et al. (2019a)