Table 4.
Genotype distribution of rs1840680 and rs2305619 in PTX3 according to clinical characteristics and outcome
| Variable | rs1840680 (PTX3) | rs2305619 (PTX3) | ||||
|---|---|---|---|---|---|---|
| AA (n = 66) | AG + GG (n = 430) | p value | AA (n = 96) | AG + GG (n = 400) | p value | |
| Lower systolic pressure (mmHg), median (IQR) | 101.5 (94.7–110.0) | 100 (91.25–110.00) | 0.326 | 100 (94–110) | 100 (91–110) | 0.634 |
| Lower diastolic pressure (mmHg), median (IQR) | 61.5 (59.2–72.7) | 60 (58–70) | 0.370 | 60.00 (56.25–76.00) | 60 (58–70) | 0.636 |
| Higher respiratory rate (RPM), median (IQR) | 25 (22–31) | 27 (23–32) | 0.133 | 26 (23–32) | 26 (23–32) | 0.802 |
| Lower O2 saturation (%), median (IQR) | 90.5 (88.7–93.0) | 90 (88–93) | 0.738 | 90.00 (87.25–93.00) | 90.5 (88.0–93.0) | 0.713 |
| Length of hospital stay (days), median (IQR) | 3.50 (2–7) | 6 (3–12) | 0.004 | 5 (3–10.75) | 5 (3–12) | 0.298 |
| Death (n, %) | 7 (10.6) | 63 (14.7) | 0.452 | 14 (14.6) | 56 (14.0) | 0.871 |
Significant values (p < 0.05) are highlighted in bold. IQR: interquartile range; mmHg, millimeters of mercury; O2, oxygen; RPM: respirations per minute