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. 2022 Oct 28;13:20406207221132346. doi: 10.1177/20406207221132346

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© The Author(s), 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Optimization of AML ELN-2017 risk stratification based on ICAM2 expression. (a–c) High expression of ICAM2 is associated with poor prognosis in the intermediate-risk AML and combined with ICAM2 expression improved ELN2017 risk stratification into two groups. (d–f) The possibility and accuracy of ICAM2 to optimize ELN-2017 risk stratification was verified in the TCGA-AML cohort. (g–i) TCGA-AML cohort showed that ICAM2 could not distinguish disease-free survival (DFS) in the intermediate-risk group, but the improved ELN-2017 stratification had a good predictive effect on DFS.