Table 1.
Univariate and multivariate Cox regression for intermediate-risk stratification with AML.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Gender (male versus female) | 1.0143 | 0.6630–1.5518 | 0.9478 | |||
| Age (⩾60 versus <60 years) | 2.2094 | 1.4315–3.4100 | 0.0003 | 1.8418 | 1.1486–2.9532 | 0.0112 |
| WBC (⩾50 × 109 versus <Negative) | 1.4126 | 0.7638–2.6123 | 0.2708 | |||
| FLT3-ITD (Positive versus Negative) | 1.7145 | 1.0647–2.7611 | 0.0266 | 1.5551 | 0.5542–4.3642 | 0.4016 |
| NPM1 (Positive versus Negative) | 1.5553 | 0.9352–2.5866 | 0.0888 | 1.1198 | 0.3703–3.3864 | 0.8412 |
| Transplant (yes versus no) | 0.3044 | 0.1788–0.5180 | <0.0001 | 0.3674 | 0.2112–0.6390 | 0.0004 |
| ICAM2_status (high versus low) | 2.0038 | 1.2426–3.2314 | 0.0044 | 1.97 | 1.2130–3.1997 | 0.0061 |
CI, confidence interval; HR, hazard ratio; WBC, white blood cell.
Variables with p < 0.1 in the univariate analysis were included in the multivariate analysis. The p-value in bold type denotes a significant difference (p < 0.05).