Table 2.

Baseline serum parameters of iron metabolism in the exploratory and replication cohorts

Characteristic	Exploratory population (n = 200)	Replication population (n = 628)	Reference ranges
Ferritin (ng/mL)	Male: 862 (307–1,574) Female: 497 (260–853)	Male: 827 (353–1,577) Female: 692 (275–1,310)	Male: 30–400 Female: 13–150
Transferrin (mg/dL)	93 (72–128)	123 (91–168)	200–360
TSAT (%)	69 (40–86)	58 (34–82)	25–45%
Iron (μmol/L))	13.8 (9.6–18.3)	16.5 (11.4–22.7)	5.8–35
Hepcidin (ng/mL)	9.0 (3.2–22.7)	12.4 (4.6–26.0)	NA

Data are presented as median and interquartile range. Baseline serum parameters were available in 828 patients, who were randomly divided into the exploratory and replication subgroup.

NA, not available; TSAT, transferrin saturation.