Table 4.

Association between serum iron indices and 90-day mortality

Characteristic	Exploratory population (n = 200)	Replication population (n = 628)
Ferritin (ng/mL)	526 (233–1,296) vs 857 (470–1709)	761 (327–1,499) vs 782 (323–1,406)
	OR 1.000, 95% CI 1.000–1.001 P = 0.01	OR 1.000, 95% CI 1.000–1.000 P = 0.86
Transferrin (mg/dL)	102 (78–135) vs 78 (61–104)	129 (96–174) vs 108 (80–142)
	OR 0.98, 95% CI 0.97–0.99 P < 0.001	OR 0.994, 95% CI 0.990–0.997 P = 0.001
TSAT (%)	65 (37–83) vs 76 (43–91)	56 (33–81) vs 68 (39–87)
	OR 1.02, 95% CI 1.003–1.027 P = 0.01	OR 1.01, 95% CI 1.002–1.017 P = 0.01
Serum iron (μmol/L)	13.8 (9.3–18.6) vs 14.0 (10.4–18.0)	16.8 (11.4–23.1) vs 15.3 (11.4–21.4)
	OR 0.98, 95% CI 0.94–1.03 P = 0.46	OR 0.98, 95% CI 0.96–1.01 P = 0.16
Hepcidin (ng/mL)	8.0 (2.5–18.9) vs 12.4 (5.1–29.9)	12.6 (4.7–26.3) vs 12.0 (4.5–24.1)
	OR 1.01, 95% CI 0.999–1.027 P = 0.07	OR 1.000, 95% CI 0.99–1.01 P = 0.98

Baseline serum parameters were available in 828 patients, who were randomly divided into the exploratory and replication subgroup. Data obtained from 90-day survivors vs nonsurvivors are shown as medians and interquartile ranges.

CI, confidence interval; OR, odds ratio; TSAT, transferrin saturation.