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. 2022 Oct 31;12(48):31004–31015. doi: 10.1039/d2ra03703c

Fig. 1. Illustration of the role of MCM7 in DNA replication. MCM7 forms a hexameric ring with the other MCM complex members that bind to DNA and assist the replication pathway. GINS and CDC45 collectively form the CMG complex that helps to catalyze the helicase activity of the complex. The origin of replication forks in the double-stranded DNA at origin, and synthesis by DNA polymerases occurs upon DNA unwinding.

Fig. 1