Figure 2.

Prevalence and evolution of escape mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after sotrovimab treatment. Detected amino acid exchanges in the spike protein at positions 337 and 340 on day 0, day 7, and day 14 after sotrovimab administration. The frequency of reads in % is indicated by the color scale. The determined patient-related SARS-CoV-2 variant is shown. Only patients with detected mutations after sotrovimab treatment are indicated. Patients selecting a spike protein mutation after day 14 are not included in this figure (patient 51).