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. 2022 Oct 6:ciac663. doi: 10.1093/cid/ciac663

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Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 1. — Comparison of clinical laboratory and virologic measurements across the groups. Lines represent median and points represent individual results. The 2 longitudinal patients are identified by an open triangle and open diamond, respectively. The open square represents the coronavirus disease 2019 (COVID-19) rebound patients who did not receive nirmatrelvir-ritonavir. Clinical values for C-reactive protein (A), absolute neutrophil count (B), and absolute lymphocyte count (C) across the acute, rebound, and late presenting COVID-19 cohorts. Severe acute respiratory syndrome coronavirus 2 cycle threshold from nasal swab samples (D) and serum nucleocapsid Ag (E). Cycle threshold was not available at rebound time point for longitudinal patient 1 (diamond) as it was run on a BioFire platform. Abbreviation: Ag, antigen.