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. 2022 Oct 6:ciac663. doi: 10.1093/cid/ciac663

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Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 2. — Viral sequencing of severe acute respiratory syndrome coronavirus 2 isolated from acute and rebound groups compared with Omicron BA.2 subvariant. A, Nucleotide mutations in the sequenced isolates from the acute and rebound groups compared with Omicron BA.2 subvariant. Vertical dashes for each isolate correspond to changes from the Omicron BA.2 subvariant. Zoomed images of the nsp5 region and the spike region are shown from isolates from the acute group (HES-CS-9, HES-CS-154, HES-CS-124, and HES-CS-151-1) and rebound group (HES-CS-144-2, HES-CS-147, HES-CS-140, HES-CS-150, and HES-CS-151-2) with specific mutations labeled. B, Longitudinal sequencing data for patient 1. Abbreviations: aa, amino acid; nt, nucleotide.