Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 6:ciac663. doi: 10.1093/cid/ciac663

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure 3. — Comparison of antibody level measurements across the groups. Antibody levels by enzyme-linked immunosorbent assay (ELISA) against the spike protein (A), spike–receptor binding domain (RBD) (B), and the nucleocapsid protein (C) presented as OD. ELISA data not available for longitudinal patient 1 (diamond), 1 acute patient, and 1 rebound without nirmatrelvir-ritonavir patient (square). sVNT to detect neutralizing antibodies against the wild-type (D) and Omicron (E) spike protein presented as percent binding inhibition. Dotted lines represent the cutoff for a positive result for the antibody tests (A–C). Mann–Whitney test was used to derive P values comparing the acute and rebound coronavirus disease 2019 cohorts. Abbreviations: Ig, immunoglobulin; OD, optical density; RBD, receptor-binding domain; sVNT, surrogate viral neutralization test.