Figure 3.

CD4⁺ and CD8⁺ T cell responses to SARS-CoV-2 peptides in antibody high and antibody no/low RAIRD patients. (A) Spike-specific CD4⁺ T cells were significantly higher in the antibody high patients and there were no detectable nucleocapsid-specific CD4⁺ T cells. (B) No difference in total cytokine-positive spike-specific CD4⁺ T cells. (C) Cytokine patterns expressed by spike and nucleocapsid-specific CD4⁺ T cells. (D) Higher spike-specific CD8⁺ T cells in antibody high patients. (E) No difference in total cytokine-positive spike-specific CD8⁺ T cells. (F) Cytokine patterns expressed by spike and nucleocapsid-specific CD8⁺ T cells