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. 2022 Oct 18;65(20):14180–14200. doi: 10.1021/acs.jmedchem.2c01373

Table 2. Isothermal Titration Calorimetry of LecB with Fucosyl Benzamides β-4a and α-6a.

compound ΔG [kJ mol–1] Kd [nM] n ΔH [kJ mol–1] TΔS [kJ mol–1]
4a –38.6 195 ± 97 1.0 ± 0.1 –29.4 ± 1.3 9.2 ± 0.4
6 –32.2 2310 ± 350 0.9 ± 0.1 –28.0 ± 1.7 4.2 ± 1.3
a

Means and std. dev. were calculated from three independent titrations.