A-B. Micrograph of luminal mucus and debris showing relatively large-sized Candida-immunoreactive yeast forms and scattered pseudohyphae (A, arrows) in association with true hyphae (mycelia) (B), consistent with C. albicans.
C-D. Representative micrographs showing smaller yeast forms in intestinal lumen (C) and glands (D), not accompanied by hyphal forms, suggestive of non-albicans Candida species.
E-F. Intestinal lumen entirely occupied by masses of relatively small Candida yeasts (E), linearly arranged around the base of the colonic glands in areas with intact epithelium.
(A-F: anti-Candida DAB immunostaining with hematoxylin counterstain. All: original magnification: x600).