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. 2022 May 17;39(7):110811. doi: 10.1016/j.celrep.2022.110811

Figure 1.

Figure 1

Cilia in the developing human telencephalon

Coronal sections of the 8 PCW telencephalon immunostained with the indicated markers.

(A and D) SOX2 expression in dorsal and ventral telencephalic progenitors.

(B, C, E, and F) PAX6 and TBR1 expression are confined to dorsal progenitors and neurons, respectively.

(G–L) GSX2 (G and J), DLX2 (H and K), and OLIG2 (I and L) expression are confined to the ventral telencephalon.

(M–O) ARL13B+ cilia projecting from progenitor cells into the ventricular lumen in the dorsal (M) and ventral (O) telencephalon. Note the absence of ARL13B expression in TBR1+ projection neurons (N).

ctx, cortex; LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence; SVZ, subventricular zone; VZ, ventricular zone. Scale bars, 500 μm (A), 100 μm (D), and 2.5 μm (M). See also Figure S1.