TABLE 1.
Study | Type of study | COVID-19 stage | Sample size (E/C) | Age (M ± SD) (E/C) | Treatment |
Dose/Frequency (SFJD) | Durations | |
Intervention | Control | |||||||
Yan et al. (25) | RCT | Ordinary | 50/50 | 60.26 ± 7.32/59.48 ± 8.24 | SFJD + interferon alpha + arbidol | Interferon alpha + arbidol | 2.08 g/times, tid | 14 days |
Zhang et al. (33) | RCT | Mild | 117/117 | 41.7 ± 9.9/41.2 ± 13.9 | SFJD + conventional therapy |
Conventional therapy | 2.08 g/times, tid | 7 days |
Chen et al. (30) | Cohort study | Ordinary | 34/34 | 65.06 ± 10.63/64.35 ± 10.34 | SFJD + conventional therapy |
Conventional therapy | 2.08 g/times, tid | 7 days |
Qu et al. (28) | Cohort study | Mild and ordinary | 40/40 | 39.65 ± 11.20/41.60 ± 10.50 | SFJD + arbidol + conventional therapy | Arbidol + Conventional therapy | 2.08 g/times, tid | 10 days |
Wu et al. (27) | Case series | Ordinary | 44 | 43.04 ± 15.33 | SFJD + conventional therapy | 2.08 g/times, tid | 3–7 days | |
Chen et al. (32) | Cohort study | Ordinary | 100/100 | 60.2 ± 6.6/60.4 ± 6.6 | SFJD + arbidol | Arbidol | 2.08 g/times, tid | 14 days |
Xia et al. (31) | Cohort study | Mild and ordinary | 43/33 | 46.95 ± 14.9/45.9 ± 13.3 | SFJD + antiviral drugs (umifenovir /lopinavir/ritonavir tablets) |
Antiviral drugs (umifenovir/ lopinavir/ritonavir tablets) |
2.08 g/times, tid | Within 3 week |
Guo et al. (34) | Case series | Ordinary and severe | 11 | 40.5 (13.5–66) | SFJD + antiviral drugs (abidor/umifenovir/lopinavir tablets) | / | / | |
Qu et al. (29) | Cohort study | Mild and ordinary | 40/30 | 40.65 ± 8.23/39.82 ± 6.40 | SFJD + arbidol + conventional therapy | Arbidol + conventional therapy | 2.08 g/times, tid | 10 days |
Xiao et al. (26) | Non-RCT | Mild | 100/100 | 69.90 ± 8.70/62.20 ± 7.50 | SFJD + arbidol | Arbidol | 2.08 g/times, tid | 14 days |
E, Experiment group; C, Control group; M, Mean; SD, Standard Deviation; SFJD, Shufeng Jiedu capsule; tid, three times a day; RCT, Randomized controlled trial.