. 2022 Oct 17;10:939157. doi: 10.3389/fped.2022.939157

Table 4.

Comparison of liver structure and function.

Characteristic	Normal	Mild	Moderate	Severe	P
TBIL[µmol/L, P50 (P25, P75)]	16.70 (9.30, 28.30)	15.20 (10.90, 28.30)	14.10 (9.10, 17.70)	15.60 (10.20, 23.50)	0.721
DBIL[µmol/L, P50 (P25, P75)]	5.20 (3.20, 6.60)	2.70 (2.70, 5.80)	3.30 (2.30, 5.10)	3.30 (2.50, 5.60)	0.686
IBIL[µmol/L, P50 (P25, P75)]	11.30 (6.10, 16.40)	11.50 (8.10, 20.90)	10.60 (6.90, 14.30)	11.20 (6.90, 16.40)	0.720
TBA[µmol/L, P50 (P25, P75)]	5.50 (3.60, 6.60)	13.00 (8.22, 16.00)^a	19.50 (5.80, 16.00)	8.70 (5.72, 14.10)	0.034
AST [U/L, P50 (P25, P75)]	24.00 (19.00, 30.00)	27.00 (20.05, 33.50)	30.00 (25.50, 38.00)	32.00 (22.00, 51.00)	0.640
ALT[U/L, P50 (P25, P75)]	14.00 (10.00, 26.00)	16.00 (12.00, 22.50)	20.00 (16.50, 47.00)	35.00 (16.00, 59.00)^a ^b	0.005
Hepatomegaly n, (%)	2 (18.2)	6 (35.3)	9 (52.9)	23 (59.0)	0.070

TBIL, total bilirubin. DBIL, direct bilirubin. IBIL, indirect bilirubin. TBA, total bile acid. AST, Aspartate aminotransferase. ALT, Alanine aminotransferase.

^{^a}

Means when compared with the normal group, P < 0.05.

^{^b}

Means when compared with the mild group, P < 0.05.