Table 3.

Top 20 CpG sites with sex differences in DNA methylation.

Gene Name	CpG Site	P-value (unadjusted)	FDR P-value	Mean Methylation Difference (%, Male-Female)
ATP5J	cg17612569	9.14E-111	2.74E-105	23.48
CCT7	cg06642617	3.41E-48	2.32E-44	5.25
YARS2	cg01225095	2.97E-40	7.80E-37	−3.74
FASTKD2	cg11065518	2.92E-35	3.47E-32	−1.56
GLUD1	cg22227586	2.77E-34	2.76E-31	−5.41
TOMM40	cg12266551	5.80E-31	3.45E-28	−3.34
CLYBL	cg27053299	1.29E-30	7.21E-28	−4.22
CLYBL	cg05833851	1.42E-28	5.83E-26	−3.45
NDUFA13	cg25274157	5.64E-27	1.78E-24	−4.04
LACTB2	cg19632760	3.29E-22	4.82E-20	−3.55
BOLA1	cg24364827	6.03E-22	8.44E-20	−3.65
NDUFA13	cg03233793	3.97E-21	4.83E-19	−3.87
MACROD1	cg01882150	2.40E-20	2.60E-18	−1.57
C15orf40	cg24717799	3.40E-19	3.07E-17	−4.39
PTGES2	cg22863798	8.27E-19	7.02E-17	1.55
NDUFA13	cg07624705	9.15E-19	7.72E-17	−3.46
SFXN5	cg07452306	1.28E-18	1.06E-16	−2.45
NDUFA13	cg08331981	1.61E-18	1.31E-16	−3.43
PKLR	cg03314840	6.96E-18	5.13E-16	−3.11
ATP5G2	cg02905198	3.31E-17	2.19E-15	−2.80