FIGURE 7.
(a and b) Relative CDKN2A and HDAC10 expression in parental and CASP8AP2 knockout HEK293 cells determined in a GAPDH-normalized real-time quantitative polymerase chain reaction. (c) Effect of overexpressing CDKN2A on luciferase activity in parental (parental CDKN2A) and CASP8AP2 knockout (892–7 CDKN2A) HEK293 cells (*p < .05). (d) Effect of CDKN2A overexpression on cell growth of the parental cell line. Results represent the average of at least three biological replicates, with error bars representing standard deviation