TABLE 2.
Descriptive characteristics of study participants
| Overall sample | No child filaggrin mutation | Yes child filaggrin mutationa | ||
|---|---|---|---|---|
| Sample size (N) | 624 | 575 | 49 | |
| Continuous variables | median (interquartile range) | p-valueb | ||
| Breastmilk months | 7.00 (2.00, 12.75) | 7.00 (2.00, 12.63) | 5.38 (1.52, 13.00) | .86 |
| Age of introduction of solid foods (months) | 6.00 (5.00, 6.00) | 6.00 (5.00, 6.00) | 6.00 (4.00, 6.00) | .73 |
| Categorical variables | n (%) | p-valuec | ||
| Maternal diet index ≥median | 312 (50) | 281 (50) | 31 (63) | .07 |
| Gestational smoking | 56 (9) | 50 (9) | 6 (12) | .43 |
| Nulliparous | 314 (50) | 286 (50) | 28 (57) | .37 |
| Maternal history of asthma | 101 (16) | 91 (16) | 10 (20) | .42 |
| Mode of delivery—vaginal | 491 (79) | 453 (79) | 38 (78) | .86 |
| Child’s race/ethnicity | .67 | |||
| Non-Hispanic White | 323 (52) | 293 (51) | 30 (61) | |
| Non-Hispanic Black | 77 (12) | 72 (13) | 5 (10) | |
| Hispanic | 147 (24) | 138 (24) | 9 (18) | |
| Otherd | 77 (12) | 72 (13) | 5 (10) | |
| Child’s sex—female | 295 (47) | 270 (47) | 25 (51) | .66 |
a
Children were classified as having a filaggrin mutation if they had a non-wildtype genotype for any of the following filaggrin mutation variants: R501X, S3247X, R2447X, 2282del4, p.S3316X, and p.R826X.
b
Group differences were assessed using the nonparametric Wilcoxon rank-sum tests.
c
Group differences were assessed using the Fisher’s exact tests.
d
Other race/ethnicity includes Asian, American Indian/Alaska Native, Hawaiian/Pacific Islander, and multiracial.