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Tumor size change from baseline over time, by RECIST. Lines represent individual patients. Dashed horizontal reference lines at 20% and –30% indicate the thresholds for RECIST V.1.1-defined objective progression and partial response, respectively. (A) Dose escalation and (B) dose expansion. HNSCC, head and neck squamous cell carcinoma; NSCLC, non-small cell lung cancer; RECIST, Response Evaluation Criteria in Solid Tumors.
