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. 2022 Feb;50(2):168–173. doi: 10.1124/dmd.121.000646

TABLE 1.

Model estimates for log transformed naltrexone biotransformation in non-UMB samples, adjusted for source (R2 = 0.36).

Variable Beta 95% CI Beta (in SD Units) 95% CI P Value
Age (in decades) 0.09 0.01 to 0.17 0.42 0.06 to 0.78 0.024
Age squared −0.08 −0.26 to 0.10 −0.36 −1.15 to 0.44 0.370
Female −0.05 −0.13 to 0.04 −0.21 −0.6 to 0.18 0.282
Var/wta −0.16 −0.27 to -0.05 −0.73 −1.23 to -0.24 0.004
Var/vara −0.59 −0.83 to -0.35 −2.66 −3.76 to -1.56 <0.001

*Var: co-occurring rs3829125 and rs17134592