Table 1. Clinical characteristics of the donors that passed the screening.
| Donor No. | Age | Sex | BMI (kg/m2) | HbA1c (mmol/mol) | Pancreas region frozen biopsies | IA2A | GADA | Cause of death | |
|---|---|---|---|---|---|---|---|---|---|
| NDs | ND-1 | 13 | M | 16 | 40 | tail | na | na | Celebral anoxia due to cardiac arrest |
| ND-2 | 35 | F | 24.7 | na | body | - | - | Hypoxemia due to cardiac arrest | |
| ND-3 | 57 | F | 22.7 | 45 | tail | na | na | Subarachnoid hemorrage | |
| ND-4 | 45 | F | 25.4 | 38.8 | tail | - | - | Infarction in the cerebellum | |
| ND-5 | 21 | M | 28 | 38.8 | tail | - | - | Head trauma | |
| ND-6 | 17 | F | 28.9 | na | body | na | na | Traumatic subarachnoid hemorrage | |
| ND-7 | 63 | M | 24 | 39.9 | tail | - | - | Subarachnoid hemorrage | |
| ND-8 | 13 | M | 19.7 | 33 | tail | - | - | Strangulation | |
| Mean | 33 | 23.7 | 39.3 | ||||||
| T1Ds | T1D-1 | 16 | M | 21.9 | na | tail | na | na | Trauma subarachnoid hemorrage |
| T1D-2 | 36 | F | 20.9 | 55.2 | tail | na | na | Intracranial hemorrage | |
| T1D-3 | 60 | F | 23.9 | 66.1 | tail | + | + | Subarachnoid hemorrage | |
| T1D-4 | 47 | F | 27.6 | 57.4 | body | - | - | Cardiac arrest | |
| T1D-5 | 24 | M | 27.5 | 67.2 | tail | + | - | Trauma | |
| T1D-6 | 25 | F | 26.7 | 54.1 | tail | - | - | Cerebral edema due to hypoglycemia | |
| T1D-7 | 65 | M | 24.2 | na | tail | na | na | Trauma by fall | |
| Mean | 39 | 24.7 | 60 |
During the screening, donors with a pronounced immune cell infiltration, or biopsies consisting mainly of fibrotic or adipose tissue were excluded from the study. All islets in donors with T1D were insulin-negative. NDs: Non-diabetic subjects, T1Ds: Type 1 diabetic subjects. Na: not available. +: present, -: not present.